Products
ICAM-1 antibody
- Product Name
- ICAM-1 antibody
- Catalogue No.
- FNab04103
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG1
- Clone ID
- 7F11
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- intercellular adhesion molecule 1
- Alternative Names
- BB2 antibody, CD54 antibody, ICAM 1 antibody, ICAM1 antibody, ICAM-1 antibody, P3.58 antibody
- UniProt ID
- P05362
- Observed MW
- 85-95 kDa
Application
- Tested Applications
- ELISA, IHC, WB, FC
- Recommended dilution
- WB: 1:1000-1:4000; IHC: 1:50-1:500
Validated Images
Raji cells were subjected to SDS PAGE followed by western blot with FNab04103(ICAM-1 Antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab04103(ICAM-1 Antibody) at dilution of 1:50.heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
- Background
- ICAM-1 (CD54) is a 90-kDa transmembrane glycoprotein of the immunoglobulin superfamily and is critical for the firm attachment and transmigration of leukocytes out of blood vessels and into tissues (PMID: 19307690). ICAM-1 is expressed by several cell types, typically on endothelial cells and cells of the immune system, and its expression can be up-regulated by various stimuli, including TNF-α, INF-γ, IL-1 and thrombin (PMID: 3086451; 9694714; 15979056). It is a ligand for LFA-1 and Mac-1, serves as a receptor for rhinovirus, and is one of several receptors used by Plasmodium falciparum (PMID: 2566624; 2538244; 2475784).
